OptiChallenge™ Inhibition Panel
The OptiChallenge Inhibition Panel is intended to provide a means of detecting the types of inhibition of nucleic acid amplification methods and serology assays that may be observed as the result of interfering substances commonly found in serum, plasma or whole blood specimens. The OptiChallenge Inhibition Panel members are designed to mimic the potential interfering substances and clinical conditions, such as haemolysis, icterus, and lipemia. The OptiChallenge Inhibition Panel also contains representative substances that are frequently used as drugs or anticoagulants (such as heparin) which may cause inhibition of certain assays. The OptiChallenge Inhibition Panel is for Research Use Only. Not for use in diagnostic procedures.
Procedure
The OptiChallenge Inhibition Panel is designed for use with any assay system used to detect analytes derived or stored in whole blood or blood derivatives. Accordingly, the levels of interfering substances present in each panel member are within the range observed in clinical patient specimens that are tested for many different analytes.
Although there is flexibility in the type of analytes which may be used with the panel, all OptiChallenge Inhibition Panel members, including EDTA plasma, should be spiked with an equal volume (and concentration) of the desired analyte, so that the interference/non-interference claims of the extraction and/or assay system are consistently verified.
Product Description
Although the normal human plasma used in the manufacture of the OptiChallenge Inhibition Panel has been determined to be non-reactive for antibodies to HIV-1 and HIV-2, antibodies to HCV, Hepatitis B Surface Antigen (HBsAg) and antibodies to Syphilis, it should be handled as if capable of transmitting infectious agents.
This product contains 0.05% sodium azide and 0.05% gentamicin sulfate as preservatives.
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Control Configurations
| Description | Catalog Number |
|---|---|
| 95-6400 | EDTA Plasma (1 vial, 1.0 mL) |
| Haemolytic Blood Low (1 vial, 1.0 mL) |
|
| Haemolytic Blood Mid (1 vial, 1.0 mL) |
|
| Haemolytic Blood High (1 vial, 1.0 mL) |
|
| Heparinized Plasma (1 vial, 1.0 mL) |
|
| Lipemic Plasma (1 vial, 1.0 mL) |
|
| Icteric Plasma (1 vial, 1.0 mL) |
Each control is filled into sterile 2 mL polypropylene vials with screw caps. OptiChallenge™ Inhibition Panel is shipped frozen on dry ice packs.
Storage Instructions
It is recommended that the OptiChallenge Inhibition Panel be stored at -20°C to -85°C to ensure highest quality. Panel members may be refrozen after first use, thawed and used a second time with minimal loss of activity. Discard any unused material after the second use.
